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Automated localisation of the optic disc, fovea, and retinal blood vessels from digital colour fundus images

机译:从数字彩色眼底图像自动定位视盘,中央凹和视网膜血管

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摘要

AIM—To recognise automatically the main components of the fundus on digital colour images.
METHODS—The main features of a fundus retinal image were defined as the optic disc, fovea, and blood vessels. Methods are described for their automatic recognition and location. 112 retinal images were preprocessed via adaptive, local, contrast enhancement. The optic discs were located by identifying the area with the highest variation in intensity of adjacent pixels. Blood vessels were identified by means of a multilayer perceptron neural net, for which the inputs were derived from a principal component analysis (PCA) of the image and edge detection of the first component of PCA. The foveas were identified using matching correlation together with characteristics typical of a fovea—for example, darkest area in the neighbourhood of the optic disc. The main components of the image were identified by an experienced ophthalmologist for comparison with computerised methods.
RESULTS—The sensitivity and specificity of the recognition of each retinal main component was as follows: 99.1% and 99.1% for the optic disc; 83.3% and 91.0% for blood vessels; 80.4% and 99.1% for the fovea.
CONCLUSIONS—In this study the optic disc, blood vessels, and fovea were accurately detected. The identification of the normal components of the retinal image will aid the future detection of diseases in these regions. In diabetic retinopathy, for example, an image could be analysed for retinopathy with reference to sight threatening complications such as disc neovascularisation, vascular changes, or foveal exudation.


机译:目的—自动识别数字彩色图像上眼底的主要成分。方法—眼底视网膜图像的主要特征定义为视盘,中央凹和血管。描述了方法的自动识别和定位。通过自适应,局部,对比度增强对112个视网膜图像进行了预处理。通过识别相邻像素强度变化最大的区域来定位光盘。通过多层感知器神经网络识别血管,为此,输入来自图像的主成分分析(PCA)和PCA第一成分的边缘检测。使用匹配相关性以及中央凹的典型特征(例如,视盘附近最暗的区域)来识别中央凹。图像的主要组成部分由经验丰富的眼科医生确定,以与计算机方法进行比较。结果:识别每个视网膜主要成分的敏感性和特异性如下:视盘为99.1%和99.1%;血管分别为83.3%和91.0%;中央凹的占80.4%和99.1%。结论—在这项研究中,可以准确地检测出视盘,血管和中央凹。视网膜图像正常成分的识别将有助于将来在这些区域中检测疾病。例如,在糖尿病性视网膜病中,可以参考视力复杂性(例如椎间盘新血管形成,血管变化或中央凹渗出)分析图像的视网膜病变。

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